Healthcare Professional Frequently Asked Questions
What is Humatrope®?
Humatrope is a synthetic form of human growth hormone. Humatrope's structure and chemistry are identical to those of the growth hormone produced by the human pituitary gland. Humatrope is biosynthesized through a process known as recombinant DNA technology. In the United States, Humatrope was the first commercially available human growth hormone that is identical to endogenous growth hormone.
Why must patients inject Humatrope?
Humatrope is a protein. If it were taken orally, Humatrope would be digested in the stomach. Humatrope must be injected to be properly absorbed and remain active.
What can your patients expect from Humatrope therapy?
Response to Humatrope therapy varies between individuals. Some studies suggest that several months of treatment may be necessary for an adequate response.
When is the best time of day for patients to inject Humatrope?
Growth hormone normally is produced at peak levels when people are asleep. Accordingly, it is usually recommended that growth hormone be given in the evening to imitate what happens naturally in the body. However, there may be reasons to give the injection at other times of the day in certain cases.
What happens if your patients forget to take a dose?
If a patient misses a dose of Humatrope, they should simply take their next dose at the regularly scheduled time. Instruct them to not double up on doses.
How should your patients store Humatrope?
Keep vials and cartridges of Humatrope and diluent for Humatrope in a refrigerator; do not freeze them. Before mixing, check the expiration dates. Do not use expired Humatrope or diluent. After reconstituting Humatrope, keep it in a refrigerator --- again, do not freeze it. Once mixed, Humatrope must be used within 14 days (vials) or 28 days (cartridges). Do not use any Humatrope solution if it is more than 14 days old (vials) or 28 days old (cartridges). Do not shake the Humatrope. If the Humatrope is cloudy or contains any particles or sediment, do not use it. Patients should report the situation to their Humatrope provider, who will advise them about what to do with the product. Colorless specks are okay; these are tiny molecules of protein.
How should patients travel with Humatrope?
Keep Humatrope cold (not frozen!) in a small cooler that can be carried in a car or on-board an airplane. However, do not check the cooler as baggage - keep it with you at all times. Coolers are available by calling Lilly at 1-800-LillyRx, or 1-800-545-5979.
