About growth

There is a wide range of normal heights during childhood. See below for examples* of normal height ranges at different ages.

Humatrope for children 2 years of age

2 Years of Age

Boys: About 32.0 to 37.0 inches

Girls: About 31.0 to 36.5 inches

Humatrope for children 5 years of age

5 Years of Age

For both boys and girls:

About 39.0 to 46.0 inches

Humatrope for children 10 years of age

10 Years of Age

Boys: About 49.5 to 60.0 inches

Girls: About 49.5 to 59.5 inches

Humatrope for children 15 years of age

15 Years of Age

Boys: Boys: About 61.0 to 72.5 inches

Girls: About 59.0 to 68.5 inches

*Examples use the 3rd and 97th percentiles for US children as the upper and lower limits of the normal range.

SELECT SAFETY INFORMATION

  • Do not take Humatrope if you are having serious complications after having open heart surgery, abdominal surgery, or serious injuries involving many body systems, or are having life-threatening breathing problems. Deaths have been reported in such cases.

How is growth measured?

Regular, accurate measurements of weight and height are an important part of a child's health care. In infancy, length and weight should be regularly checked at doctor visits. During early childhood, measurements are usually taken about twice each year, and more often if there is anything unusual about a child's growth.

Growth Charts

Growth Charts

To see if your child is growing normally, your doctor will compare your child's growth to other children of the same age and sex. Growth charts showing the averages and normal ranges for height, weight, weight-to-height ratio, and head size of children at different ages are used to check your child's growth over time.

Download growth chart for boys

Download growth chart for girls

Stadiometer

Stadiometer

Throughout a child's school years, it is helpful to collect accurate measurements at least once a year. Among the many ways to measure height and weight, doctors and nurses generally use an instrument called a stadiometer for accurate height measurements. A stadiometer is a carefully engineered device used to obtain accurate height measurements. A stadiometer typically has a vertical ruler with a sliding horizontal rod that is adjusted to rest on the top of the head.

Indications and Important Safety Information
Indications

Humatrope® (somatropin for injection) is used to treat:

  • Children who do not make enough growth hormone on their own, have short stature associated with Turner syndrome, or have SHOX deficiency; have idiopathic short stature, which means they are shorter than 98.8% of other children of the same age and sex, are growing at a rate not likely to allow them to reach normal adult height, and for whom no other cause of short stature can be found; were born smaller than normal for the number of weeks of pregnancy and who do not catch up in height by 2 to 4 years of age.
  • Adults who have growth hormone deficiency that began either in adulthood (as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma) or in childhood. Patients treated for growth hormone deficiency in childhood whose bones have stopped growing should be reevaluated to determine if they should continue growth hormone.

IMPORTANT SAFETY INFORMATION FOR HUMATROPE

What is the most important information I should know about Humatrope?

  • Do not take Humatrope if you are having serious complications after having open heart surgery, abdominal surgery, or serious injuries involving many body systems, or are having life-threatening breathing problems. Deaths have been reported in such cases.
  • Do not use Humatrope in children with Prader-Willi syndrome who are severely obese or have a history of blocked upper airways or other severe breathing problems, or sleep apnea. Deaths have been reported in such cases. Humatrope is not approved for the treatment of patients with Prader-Willi syndrome.
  • Do not use Humatrope if you have active cancer. Growth hormone deficiency can be an early sign of some tumors in the brain or pituitary gland. The presence of these types of tumors should be ruled out by your doctor before you start Humatrope.
  • Serious allergic reactions have been reported with Humatrope. Humatrope is contraindicated if you know you have allergies to growth hormone or any of its ingredients. Tell your doctor if you have an allergic reaction. Do not mix Humatrope with the supplied diluent if you are allergic to metacresol or glycerin.
  • Your doctor should check your blood sugar regularly while you are taking Humatrope, especially if you have diabetes, pre-diabetes, or risk factors for diabetes. New cases of type 2 diabetes have been reported in patients taking Humatrope.
  • Tell your doctor if you have any visual changes accompanied by headache, nausea, and/or vomiting while taking Humatrope. This may be a sign of increased pressure in the brain.
  • Adults may retain water during Humatrope treatment. This may be brief and may increase with higher doses of Humatrope.
  • If you have hypoadrenalism and are on glucocorticoid replacement therapy, your doctor may increase your dosage when you initiate growth hormone treatment.
  • Your doctor should test your thyroid function periodically during Humatrope therapy. Thyroid hormone treatment may need to be started or adjusted.
  • Fracture in the ball of the hip joint can occur in children who have endocrine problems and in children who have rapid growth. Any child taking Humatrope who develops a limp or complains of hip or knee pain should be seen by a doctor to check for this.
  • Progression of curvature of the spine (scoliosis) can occur in children who have rapid growth. Humatrope has not been shown to increase the occurrence of this condition. If the child has scoliosis, the doctor should carefully monitor the progression of the scoliosis during Humatrope treatment.
  • Cases of pancreatitis (inflammation of the pancreas) have been reported rarely in children and adults receiving growth hormone. Consult a doctor if you develop abdominal pain while taking Humatrope.
  • You should rotate your injection sites to avoid breakdown of skin and fat. Seek prompt medical attention for any allergic reaction you experience to the injection of Humatrope.

WHO SHOULD NOT TAKE HUMATROPE

Who should not take Humatrope?

Humatrope should not be used by:

  • People with serious complications after having open heart surgery, abdominal surgery, serious injuries involving many body systems, or with life-threatening breathing problems
  • Children with Prader-Willi syndrome who are severely obese or have a history of severe breathing problems
  • People with active cancer
  • People who have had an allergic reaction to growth hormone
  • People with diabetic disease of the retina (the lining in the back of the eyeball)
  • Children who have closed growth plates in their bones
TALK TO YOUR DOCTOR

What should I tell my doctor before taking Humatrope?

Tell your doctor about all of your prescription and over the counter drugs, including cyclosporine, hormone replacement therapy, insulin or other diabetes medications, drugs containing steroids, or drugs for seizures. These medications may need to be adjusted while taking Humatrope.

COMMON SIDE EFFECTS

What are the possible side effects of Humatrope?

Common side effects reported in adults and children taking Humatrope include injection site reactions, allergic reactions to the diluent, and hypothyroidism. Additional common side effects in adults include swelling, joint pain, muscle pain, carpal tunnel syndrome, unusual skin sensations, and high blood sugar. You are encouraged to report negative side effects of prescription drugs to the Food and Drug Administration (FDA). Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

STORING HUMATROPE

How should I store Humatrope?

Humatrope must be kept refrigerated (36° to 46°F [2° to 8°C]) before and after it is mixed. Do not freeze. Once Humatrope has been mixed and is in liquid form, cartridges must be used within 28 days and vials must be used within 14 days. Throw away any unused Humatrope in a cartridge after 28 days and in a vial after 14 days. Before giving an injection, check the manufacturer’s expiration date on the cartridge or vial. Do not use the cartridge or vial if it has expired.

ADDITIONAL INFORMATION

Humatrope is available by prescription only.

Click to access Patient Information-Cartridge, Patient Information-Vial, and Full Prescribing Information.

See Full Pen User Manual that accompanies the HumatroPen® 6 mg, 12 mg, and 24 mg.

Humatrope is a registered trademark owned or licensed by Eli Lilly & Company, its subsidiaries, or affiliates.
HG CON ISI 14OCT2016